The effects of female sex hormones on urinary stone formation are not known. This study was conducted to investigate the effects of these hormones on stone formation by using an ethylene glycol EG and vitamin D-induced rat urolithiasis model.
One group was administered 0. The other three groups were administered 0. The rats in two Lonely hot girls Temecula these three groups were oophorectomized, and the rats of the remaining group underwent a sham operation on the day before the start of the four-week treatment period. One of the two oophorectomized groups was then administered a supplementation of female sex hormones 0.
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On the first day of the fifth week of the experimental period, the degree of crystal deposition was determined histologically, and the calcium content in renal tissue was measured. OPN is a matrix protein thought to be a promoter of stone formation.
The urinary oxalate excretion, crystal Beautiful couple wants sex Syracuse New York and calcium content in renal tissue and the expression of OPN-mRNA were greater in the oophorectomized rats compared with the controls, and the same parameters were inhibited by the female sex hormone supplementation. These suggest that female sex hormones can inhibit renal crystal deposition in EG-treated rats by suppressing the urinary oxalate excretion and the expression of OPN.
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Under an Elsevier user. Inhibitory effects of female sex hormones on urinary stone formation in rats.
Background The effects of female sex hormones on urinary stone formation are not known. Conclusions These suggest that female sex hormones can inhibit renal crystal deposition in EG-treated East pembroke NY wife swapping by suppressing the urinary oxalate excretion and the expression of OPN. Keywords urolithiasis. Recommended articles Citing articles 0. Published by Elsevier Inc.
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